Human Genetics

The story of how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, and how we strode out of Africa, invented farming and cities and ultimately created modern civilisation. Where did we come from? Where are we going? Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth.

Written by experts and authorities in the field and professionally narrated for easy listening, this crash course is a valuable tool both during school and when preparing for the USMLE, or if you're simply interested in the subject. The audio is focused and high-yield, covering the most important topics you might expect to learn in a typical medical school human genetics course. Included are both capsule and detailed explanations of critical issues and topics you must know to master human genetics.

There are rare moments in time when we make choices that irreversibly change the world, and our lives, forever. Today is one of those moments. Scientists, engineers and philosophers alike warn us that without a radical shift in our thinking, we are on track to be the last generation of pure humans that the world will know. Within a single generation we will devolve into a hybrid species of synthetic bodies, Artificial Intelligence (AI), and computer chips that limit our ability to think, to love, and to adapt to the conditions of the emerging world in a healthy way.

In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

We like to think of ourselves as exceptional beings, but are we really any more special than other animals? Humans are the slightest of twigs on a single family tree that encompasses four billion years, a lot of twists and turns and a billion species. All of those organisms are rooted in a single origin, with a common code that underwrites our existence. This paradox - that our biology is indistinct from all life, yet we consider ourselves to be special - lies at the heart of who we are.

Nothing is more familiar and yet less understood than the human mind. It defines the experience of being human, and yet its workings contain some of the deepest mysteries ever encountered. Written by one of the world's greatest teachers of psychology, The Human Mind provides a masterful and riveting guide to all that we have learned since modern science began probing those mysteries.

In ‘Humans Are Doomed To Go Extinct’, an article in Scientific American published in November 2021, veteran Nature editor Dr Henry Gee predicted that Homo sapiens is on a rapid one-way ride to extinction. The article provoked media coverage and comment around the world. In The Decline and Fall of the Human Empire, Gee expands the themes of his much-discussed article to book length, charting both the rise as well as the fall of humans. Gee paints a picture of extinction within the next 10,000 years – and suggests ways that our exceptional species might avoid its fate.

Some 73,000 years ago, the Mount Toba supervolcano in toda's Indonesia erupted, releasing the energy of a million tons of explosives. So much ash and debris was injected into the stratosphere that it partially blocked the sun's radiation and caused global temperatures to drop for a decade. In this book, Donald R. Prothero presents the controversial argument that the Toba catastrophe nearly wiped out the human race, leaving only about a thousand to ten thousand breeding pairs of humans worldwide.

What is human consciousness, and how is it possible? This question fascinates thinking people from poets and painters to physicists, psychologists, and philosophers. From Bacteria to Bach and Back is Daniel C. Dennett's brilliant answer, extending perspectives from his earlier work in surprising directions, exploring the deep interactions of evolution, brains, and human culture.

The study of human evolution is advancing rapidly. Newly discovered fossil evidence is adding ever more pieces to the puzzle of our past, while revolutionary technological advances in the study of ancient DNA are completely reshaping theories of early human populations and migrations. In this Very Short Introduction, Bernard Wood traces the history of paleoanthropology from its beginnings in the 18th century to the very latest fossil finds.

In A Story of Us, they present this rich narrative and explain how the evolution of our genes relates to the evolution of our cultures. Newson and Richerson take listeners through seven stages of human evolution, beginning seven million years ago with the apes that were the ancestors of humans and today's chimps and bonobos. The story ends in the present day and offers a glimpse into the future.

Humans are a puzzling species. On the one hand, we struggle to survive on our own in the wild, often failing to overcome even basic challenges, like obtaining food, building shelters, or avoiding predators. On the other hand, human groups have produced ingenious technologies, sophisticated languages, and complex institutions that have permitted us to successfully expand into a vast range of diverse environments. What has enabled us to dominate the globe, more than any other species, while remaining virtually helpless as lone individuals?

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

With so much variation that can be handed down genetically, for better or worse, the way we understand our biology holds huge importance for how we understand our world and one another, including the biggest questions of our day, such as social inequality. Eye-opening and profound, Adaptable is a revolutionary reappraisal of an overlooked science.

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

Fifty thousand years ago, we were not the only species of human in the world. There were at least four others, including the Neanderthals, Homo floresiensis, Homo luzonesis and the Denisovans. At the forefront of the latter's ground-breaking discovery was Oxford Professor Tom Higham. In The World Before Us, he explains the scientific and technological advancements.