The Switch cover art

The Switch

Activate Your Metabolism for a Healthier Life

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The Switch

By: James W. Clement, Kristin Loberg, George M. Church
Narrated by: Michael David Axtell
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About this listen

Enter autophagy, an ancient mechanism built into our cells that eliminates toxic materials, initiates fat-burning, and protects cells against stress. Best-known for being triggered by intermittent fasting, the complex process not only slows down the ageing process, but optimises biological function as a whole, staving off all manner of disease - from diabetes to dementia - and affording us the healthy lifespan we never thought possible.

So how can we activate autophagy? It’s as simple as flipping a switch. The Switch unpacks the revolutionary research on the body's natural process for maintaining health and youthfulness, as well as the “dial” that controls it. Backed by a synthesis of the data, and with a foreword by renowned Harvard geneticists Drs. George Church and David Sinclair, The Switch not only decodes the science of autophagy, but also teaches readers how to control it and benefit from its profound impact.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2019 James Clement and Kristin Loberg (P)2019 Simon & Schuster, Inc.
Aging & Longevity Hygiene & Healthy Living Personal Development Nutrition Health Healthy Diet Longevity

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All stars
Most relevant  
I was aware of fasting but was not entirely convinced about the benefits or the science vs feeling hungry. This book clearly lays out the science and benefits easily understandable to the average person. I recommend it.

Finally convinced about fasting

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I like that it has recent studies and combines various popular practices such as keto and intermittent fasting. Science based facts. Really enjoyed it and will come back to this book.

Great summary of all things important to your health

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excellent book, well worth buying, you won't regret it. a+ + + + + +

Very Informative book

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a book that persuaded me to make fundamental lifestyle changes for the better I got if for many family members

hugely informative and well reserched

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great listen, very interesting, and useful a great recommended read and will listen again and again

great listen, very interesting, and useful

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Very interesting listen.
James Clement explains the science so well and details, from a brief account of human history, how much our eating habits have changed in such a short period.

Very interesting and very well explained science

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useful information, the writers summarized thousands of reasearches and papers related to diet history and plans

informative and useful

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this was my first audio book of 2025 and what a way to start a year. I have completely changed my opinion of food and keeping my body healthy. I've changed what and how I'm eating and I feel so much better in myself. I have lots of energy and my mood is great.
The author goes into some more complex details but overall it's explained in a very easy to understand way.

very interesting start to my 2025

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Very good tips on increasing autophagy and balancing nutrients towards maximizing your health and longevity

Good read!

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unconvinced of the credentials of the author, and found contradictory info throughout where he tries to figure out what naturally long lived populations do and eat but also try to "hack" autophagy short cuts (long living Cretians that drank red wine regularly, but alcohol is only permitted once a month on the plan. Sardinians/Okinawans that eat a fairly high carb diet but not allowed carbs on this plan).
Ignores using well known populations that already fast and eat low protein diets (many Muslim populations are vegetarian but still have issues with diabetes, cancer etc) but don't live long, and instead uses weird comparisons, such as a long living whale to illustrate the benefits of eating omega 3...

There's prob a lot that is good for you here (won't argue that a diet high in veggies and fish with exercise is great), and I'm sure intermittent fasting had benefits, but it largely ignores human behaviour and what is sustainable, and only devotes about two pages to the "diet" (less than is devoted to talking about the author, how he's "read" a lot about this, was early to map his own genome - so what? - and therefore we should ignore the lack of doctorate) - and this dietary approach is a long list of what not to do or eat (no grains, no sugars, no alcohol, very little animal protein, very low carb), with very little on the "permitted" list (green veggies, omega 3 and macadamia nuts apparently).

Not one of the better books on health I've read - instead would recommend "Why we eat (too much)"

TLDR: eat pescatarian/vegan/keto to live forever

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