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Lifespan

Why We Age – and Why We Don’t Have To

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Lifespan

By: Dr David A. Sinclair, Matthew D. LaPlante
Narrated by: Dr David A. Sinclair
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About this listen

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help listeners live younger, longer.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease – it is inevitable.

But what if everything you think you know about ageing is wrong?

What if ageing is a disease? And that disease is curable.

In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan – he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick – a circuit designed to halt reproduction in order to repair damage to the genome –has enabled earth’s early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.

But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Listeners will discover how a few simple lifestyle changes – like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy – can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like – and what will need to change – when we are all living well to 120 or more.

Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. LIFESPAN is destined to be the biggest book on genes, biology, and longevity of this decade.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2019 Dr David A. Sinclair (P)2019 HarperCollins Publishers Limited
Aging & Longevity Evolution Genetics Hygiene & Healthy Living Inspiring Heartfelt Thought-Provoking Genetic Disease
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Critic reviews

‘If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant.’ – Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and #1 New York Times bestselling author

‘This is the most visionary book about aging I have ever read. Seize the day–and seize this book!’ – Dean Ornish, MD, founder & president, Preventive Medicine Research Institute, and New York Times bestselling author of UnDo It!

‘In this insightful and provocative book that asks questions about how we age, and whether humans can overcome decay and degeneration, Sinclair grapples with some of the most fundamental questions around the science of aging. The result is an elegant and exciting book that deserves to be read broadly and deeply.’ – Siddhartha Mukherjee, Pulitzer Prize–winning and #1 New York Times bestselling author

What listeners say about Lifespan

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The best audiobook up to now

I listened to a few Audible audiobooks and this is far the best! I loved how author read the book and the content is great. Sinclair presents latest science and gives profound story of his life with it. I highly recommend this book!

The book can change your views on life and give you a lot of inspiration!

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Fascinating read

I have learnt so much from this book but more than that it has instilled a sense of optimism in me I'd long ago lost. It reminded me of what can happen when human ingenuity is allowed to flourish.
I liked the fact that ethical concerns were discussed and covered and the book didn't shy away from difficult questions but rather tried to open up the conversation

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it blows me away to think what is around corner

This book makes me want to dig deeply into this area! honestly I can't wait to see what comes out of David Sinclaors lab in the future.

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enlightening and uplifting read on aging.

this is a really interesting and uplifting read about the future of humanity and how aging can be fought and hopefully stopped one day. fascinating read!

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Eye openening

Gives genuine scientific hope for a longer, healthier & happier life, giving examples of easily make able changes our species could do to achieve this goal.

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A very thought provoking read

Being very health conscious myself and wanting to thrive rather than survive in life, I found this book both confirming many of my beliefs in living a long healthy life, but also challenging others. It is a fascinating look at the future and I would highly recommend it to all. I will certainly be looking into taking NMN and other health protocols David undertakes. A great listen 👍

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Very thought provoking

An incredible book. Things can get quite technical at times but nothing the layperson (i.e. me!) can't handle. The author narrates and his soft Aussie lilt lends itself perfectly to the pace of narration. Really enjoyed this listen; a fascinating insight into the information theory of aging and the biological processes involved in growing old AND staying young. The audiobook has end-of-chapter reviews in conversation with the co-author too which are also very insightful.

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Mind blowing

The consulting adviser employed by Adam & Eve was right: eating from the tree of knowledge leads to eternal life ...

This book presents a convincing argument that aging is not an inevitability but a treatable disease. I found the book enjoyable and informative about latest scientific breakthows, as it advocates for a range of lifestyle changes such as intermittent fasting, high-intensity interval training, cold exposure, and the use of supplements such as NMN, Resveratrol, and Mitopure. Reverse aging have the potential to revolutionize the way we live, and could make a significant impact on the world our children will inherit.

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Inspiring

Insightful and so inspiring
Well read by David who is passionate about changing how we age …a must read for everyone…

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makes me hopeful and hopeless at the same time.

very well done. if it is up to me I would be subject in that lab yesterday! but please scientists like this make me so hopeful and then when I do remember humanity I lose all hope! great book everyone should listen/read ut

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